Clay Siegall follows dream, invents new class of cancer treatment drugs

Cancer treatment has traditionally entailed some of the most brutal regimes in medicine today. From radical surgery to radiation and chemotherapy, cancer treatment, since at least the 1930s, has been a torturous trial of endurance for any patient unlucky enough to receive a cancer diagnosis. Oftentimes, even the milder treatments, such as low dosage chemotherapies, will leave the patient with lasting deficits, such as neuropathy, dementia and other long-term neurological disorders.

However, there is a huge reward that has come with these terrible treatment. Cancer survival rates have increased dramatically over the last 70 years. Some cancers, which once were nearly always fatal, are now almost always curable, with five-year survival rates exceeding 99 percent. Prior to the 1930s, most diagnoses of cancer were tantamount to a death sentence. Few patients lived more than a couple of years.

Still, many types of cancer today do not have significantly better survival rates than they did 30 or 40 years ago. This is due largely to the fact that the three pillars of cancer treatment, surgery, radiation and chemotherapy essentially stopped getting better around the year 1960. While there have been certain improvements with some subtypes of cancer, many others have not seen any notable increases in survivability in the last 50 years.

But that began to change in the mid-1990s. Clay Siegall is one of the key players in developing the new class of drugs known as targeted cancer therapies. Most targeted therapies use the principle of targeting the malignancy directly, only releasing cytotoxic chemicals upon contact with the actual cancer cells. This reduces the worst side effects caused by chemotherapy, which is a medicinal blunt instrument, oftentimes releasing large amounts of poison directly into the bloodstream.

Aside from the near elimination of side effects, targeted cancer therapies are also able to dramatically increase the therapeutic window, allowing for much higher doses of cytotoxin and much more effective treatments.

Through his firm, Seattle Genetics, Dr. Siegall is continuing to develop this exciting new category of cancer treatment drugs, ensuring that the 21st century will see dramatic improvements in survivability of many subtypes of cancer.

Jose Borghi And His Unique Perspective At Mullen Lowe

Jose Borghi has a unique perspective on advertising that he uses to ensure that Mullen Lowe is prospering. There are many different people who will benefit from the services that the company offers, and they will ensure that their clients are given the best services possible. A company that wants better advertising may hire Mullen Lowe, and they may trust his staff to create better advertising for every situation.

#1: The Design Of The Company

Jose Borghi ensured that his company will be available around the world to all his clients. He knows that many of his clients are in need of help with new advertising or logos, and he will give them every opportunity to create something that is new and exciting. He knows that his clients will find a number of his ad plans to be helpful, and he will help them ensure that they make the most of this new plan to learn more: click here.

#2: The Offices

Jose has started offices around the world that will help keep their clients happy, and they will attract more companies every year that need business advertising help. These company may visit the new offices of the company, and they will feel much better knowing that the company is right there to help. Jose is keen to ensure that all his clients are given the services they need, and he wants them to be more comfortable with his company.

#3: The South American Market Is Key

The South American markets are some of the most important advertising in the world, and they are such that Mullen Lowe has prospered because of them. He has many clients in the company’s native Brazil, and he knows that it is much easier for companies to increase sales when his firm built Jose Borghi advertising.

It is important that everyone who needs services is able to work with Mullen Lowe, and the company will ensure that all companies receive the finest customer service. The service that offered through the company is much better than any other, and Jose ensures that he works directly with clients who need his help.

JHSF and José AuriemoNeto’s Dream

JHSF is well known for being the place to be in Brazilian real estate. The place for high-end shopping, international business and an airport, it is hard to find another location quite as nice as this one. They began years ago and have grown into one of the best places to be in Brazil and more information click here.

Expanding to Sao Paulo, Salvador, Manaus, Punta del Este in Uruguay and New York. The locations vary in shopping centers, restaurants and the Fasano Hotel. All of these are considered the highest level of decadence. They were all started as a dream of one man named José AuriemoNeto.

Neto is the brains behind the whole empire. A graduate of Fundaco Armando AlvaresPenteado University, he began life after graduation from the Sao Paolo school as a budding entrepreneur. First focused on commercial development, he rapidly grew the brand to be what it has become today. It wasn’t an easy accomplishment. It took years of planning, communicating with investors, merchants and other aspects of creating this enormous empire and learn more about Jose AuriemoNeto.

The most difficult aspect of what he had to accomplish was the ability to convince the merchants to put their stores, restaurants and hotels in his establishments. It’s amazing how it has grown into the amazing business that it has become. He spoke to the very best in entertainment, restaurants and shopping. His goal was to create one of the best pieces of real estate in the world. He did accomplish that for many people in the country.

Each location has a little bit of personal attention to the details which made it the place to be and be seen. Known for luxury and decadence, the shining glory of it all for many is the Fasano Hotel. It was the place to host weddings locally, have people stay that Brazilians want to impress and entertain in a very luxurious hotel. It is one of the best accomplishments for the JHSF Group. The shopping is amazing as well, with some of the best designer brands becoming available in Brazil for the first time ever. The restaurants are just as decadent and Jose’s lacrosse camp.

Patty Rocklage an Accomplished Psychotherapist

Patty Rocklage is a therapist based in Massachusetts whose primary focus is on marriage and families. She finds herself privileged to be able to help couples, individuals, and their families through their times of struggles to overcome them.

She can connect with her clients through the warm reception she provides them. She has experience of more than 20 years in the field of psychology.

In 1981, she graduated from the University of California. She is also good in several fields such as coaching, teaching, team building, public speaking, and is also active in community outreach. Patty and her husband are also great philanthropists who contribute to the political cause and numerous charities as well. Read more: Patty Rocklage | LinkedIn

Together with her husband, they have contributed funds to the Massachusetts Institute of Technology which helped in renovating the nanochemistry and nanotechnology lab. One of the Chemistry Professors Moungi Bawandeni, took Scott and Patty on a tour of the renovated labs when the project was complete. A plague was placed on the labs to honor both Scott and Patty.

Professor Bawandeni, the former department head, Silver Ceyer, and the current department head, Timothy Jamison paid their tribute. Having got his Ph.D. from the program under Richard Schrock mentorship, Scott is also an MIT alumni.

Richard Schrock was the 2005 Nobel prize winner. Moreover, Patty and her husband have also supported the Whitehead Institute and the Pittsburgh United Methodist Church.

Patty is a conservative and environmentally friendly type of a person, but she also loves a mixture of modernity and hence favors a classy lifestyle. Scott and Patty recently had their home renovated by Sudbury’s most fancied construction company. Their landscape, as well as the kitchen, was redone.

Despite being a committed wife to her husband Scott, Patty is also a devoted mother of three children. She was previously involved on the board of the Sudanese Education Fund which later changed its name to Women’s Board for South Sudanese Enrichment for families.

The organization focuses on creating employment, better education and achieving financial stability in the South Sudanese communities. She worked on the board of directors for the organization.

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Therapy Does Wonders With Patty Rocklage

Patty Rocklage Juggling Family and Career

Patty Rocklage is an accomplished psychotherapist who helps people who are struggling with marriage and family issues. She offers counseling to individuals, couples and families so that they can face their challenges.

With a psychology degree from the University of Southern California and over twenty years of experience, Dr. Rocklage is the best person to go to when looking for a psychotherapist. She is licensed by the state of Massachusetts to practice psychotherapy.

Apart from giving counseling for marriage and family, Patty Rocklage also does public speaking, coaching, team building and teaching. Read more: Pattry Rocklage | Crunchbase

The connection that Patty Rocklage has with her clients is what makes her good at her job. She understands how sensitive their issues are and hence keep their sessions confidential. She is also so warm and inviting that every person she interacts with is always at ease; this makes her patients concentrate on the change they want to achieve.


Patty Rocklage gets involved in giving back to the community from time to time. She is a volunteer in the Sudanese Education Fund that was founded to help individuals from Southern Sudan who relocates to Massachusetts.

The fund’s aim is to assist those individuals to find stable jobs and help them attain financial and education stability. In 2016, Patty together with her husband, Dr. Scott Rocklage assisted in the cost of renovating the nanotechnology and nanochemistry lab at the Massachusetts Institute of Technology’s chemistry department.

Scott Rocklage attained his Ph. D in Chemistry at that institute and that is why both of them were very pleased when they were approached to help in the project.

Patty’s family

Patty Rocklage values her family; she finds time outside her job and charitable events to spend time and do projects involving the family.

Patty and Scott Rocklage visited the Sudbury Kitchen & Bath showroom when they were thinking of renovating their family house. They hired Ed Freedlender to do the job and sat down with them to choose their preferred design.

The project was important to Patty Rocklage, so she put her valuable effort and time to make it successful for her family. She has been very successful in juggling between her career and family.

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Kate Hudson is at the Heart of Fabletics

What’s not to love about Kate Hudson? There is likely not many women who haven’t seen her treasured rom com “How to Lose a Guy in 10 Days,” amid a mass of other hits. She is also just generally like-able. She is down to Earth and just seems to resonate with women everywhere. Those qualities were some of the reasons she was chosen to be the face of unicorn athletic fashion wear brand Fabletics when it started in 2013. At the time the company was a simple startup, looking to make a name for itself in the athletic wear market. Founders knew they needed the perfect face for their brand, and Kate Hudson was definitely that face.


However, when she said yes to Fabletics, she did so with a firm commitment to not just be the face of the company, but to be wholly involved in its operations and success. She detailed her view in a recent Forbes article when she noted that she would never get behind a brand she didn’t fully believe in and would use herself. She did fully believe in Fabletics and saw the success in its horizon. From its beginning in 2013 to today Kate Hudson has been very hands on in the company. She knows exactly which pieces are doing well with her customers, which aren’t and is constantly looking for new trends and innovations to expand the product line. She also works with management and reviews numbers on a weekly basis. She notes that she will always continue to do so, as that is her business philosophy – although she will always be an actress at heart and will continue to act.


While Kate Hudson may be at the heart of Fabletics, the company’s mindset is another reason that they have grown from a startup to $250 million in sales and 1.2 million users in just 3 years. Fabletics was founded with the goal of being an innovator in the market. The company’s founders saw buyers purchase behavior evolving and knew they didn’t want to start a company that wasn’t on that cutting edge.


For that reason, Fabletics has just 22 physical locations and instead uses the technique of a reverse showroom to give buyers a great experience in today’s age of digital first. When people come to Fabletics’ site, they are greeting with a fun lifestyle quiz (check it out on their website). After taking the quiz, the entire experience is digital and is customized to the individual person’s preference. This means that there is no need to visit a physical showroom to get exactly what they are looking for every month.

Adam Goldenberg’s Big Plans For TechStyle’s Fashion Sizes

Adam Goldenberg is the cofounder and co-CEO of one of the top new apparel retailers TechStyle Fashion Group. Goldenberg said he renamed JustFab to TechStyle because the company website uses predictive analytics and big data to customize user experiences. He now wants to give women of all sizes an opportunity to wear attractive outfits and feel good about themselves, so he had all-inclusive lines launched just this last year. Goldenberg says the company values diversity and giving women a sense of self confidence and inner empowerment. TechStyle is also the parent company to ShoeDazzle, Fabletics, FabKids and FL2.

Adam Goldenberg first came to the fashion industry in 2010, but his background in marketing began back when he was only 15. At that time he built his own online company known as Gamer’s Alliance that became sought after by Intermix Media. Intermix Media asked Goldenberg to manage their marketing strategies department in 1998, and in just two years they promoted him to Chief Operating Officer at Goldenberg became good friends with another marketing guru named Don Ressler, a man who had previously been a consultant to several manufacturing and multimedia companies and had started Goldenberg and Ressler’s first company built together was Alena Media under which they also started Hydroderm.

Read more: TechStyle’s data-driven fashion – CNBC Video

Goldenberg and Ressler had a disagreement with Intermix Media’s new owners, News Corporation when they bought the company in 2005. So they left and started their own company under which they started even more brands. The fashion industry became interesting to Adam Goldenberg because while he didn’t know much about fashion, he saw a way that he could make fashion shopping even more appealing to millennials. In 2010 he and Ressler had the ideas for their new startup materialized, and it soon had many venture capital investors including Matrix Partners and Passport Capital putting funds into it.

The first notable celebrity to become a part of JustFab was Kimora Lee Simmons who loved how Goldenberg and Ressler made their company affordable to everyone while still putting out attractive apparel on She was president and creative strategy director for a few years prior to leaving. Kate Hudson joined the company around 2012 and soon began doing commercials for Fabletics. JustFab gained over $285 million by 2013 and that same year became valuated at $1 billion making it officially a unicorn. Goldenberg and Ressler decided to turn the company into something even bigger by 2014 when they started opening physical stores. Today TechStyle ships products all over the world.

Understanding the Career Trajectory of Bruce Bent II

Bruce Bent II is a successful entrepreneur and business executive who led the successful growth of The Reserve and FDIC. He is recognized for his asset management skills and also for offering cash-related solutions to banks, retail markets, broker-dealer and qualified plan. Through his inventions, Mr. Bent has transformed FDIC- Insured cash management portfolio into approximately $1 trillion industry. He has held numerous executive roles at Double Rock’s and its subsidiaries Access control Advantage LLC and Island Intellectual Property LLC. The two affiliates are today recognized as innovation leaders in their respective sectors.

Before the 208 global financial crisis, Bruce Bent II served as the President at The Reserve. Under his leadership, the firm expanded its products range and also diversified its assets under management, which grew from $4 billion and exceeded $130 billion. The Reserve had a team of over 300 employees including sales professionals. After the Lehman Brothers were declared bankruptcy in September 2008, Bruce Bent II led The Reserve to an orderly winding down of some product lines. The executive team at the firm decided to voluntarily close the product line, and shareholders of the Reserve Primary Fund were paid 99 cents on their initial investment and 100 cents on all other funds.

Things You Know about Bruce Bent II

Bruce Bent II believes that an idea can be generated by a single individual, but making it a reality would involve a team of individuals. He usually involves smart persons into his team and in some instances professionals. As an entrepreneur, Mr. Bent does not fear to fail, and when it happens he tries another route. His advice to emerging entrepreneurs is to meet and engage other individuals as they will be able build strong network of potential business partners and customers. Bruce says that entrepreneurs should be flexible and have faith in their own vision. Furthermore, they should be innovative and have expertise to divert from obstacles they face along the way.

The strategy that helps Bruce Bent II to grow and expand his business is by creating value to his customers. The executive is advising entrepreneurs to look for opportunities to exploit ways of doing business. For instance, he is encouraging homeowners to rip up their lawns and plant vegetables and fruits, or rare chickens and keep bees. This is an excellent way to start a business that can eventually grow and expand and become a source of live to many.

For more information follow Bruce Bent II on Facebook.

The Life and Career of Lori Senecal

Those who know Lori Senecal know her as a marketing executive who has a robust personality. Lori Senecal is known for her role with the Crispin Porter + Bogusky where she is the chief executive officer in charge of global operations. She has unmatched knowledge in the field of marketing and advertising. Lori Senecal is also recognized for masterminding innovative techniques when it comes to advertising. She says that she is always on her toes never staying in her comfort zone. This is something that has propelled her to the executive she has become. She managed to transform the vision and mission of CP+B. Lori is of Canadian descent and she was brought up in Montreal, Canada. She has three sisters and she is the youngest. For more details visit Forbes.

Lori Senecal is a product of education and the desire to go beyond the ordinary. For her undergraduate degree, Lori Senecal attended the McGill University. Other than English, the marketing mogul can speak French fluently. Before getting to the present position, she has worked with notable brands such as McCann Erickson, Xbox and even Coca-Cola. She has a unique capability when it comes to focusing on challenges. She is a leader who believes in talent acquisition. This means that she believes in young people and their potential. Other than the three brands mentioned above, Lori Senecal has worked with other notable companies such as HomeGoods, Vanguard, Victoria Secret Pink, and BMW. She has also been involved with American Express and Boar’s Head.

Her love for gymnastics propelled her to choose a career in marketing. During the high school and college days, she became a coach and discovered the importance of teamwork. Learning how to lead from an early age, Lori Senecal carried the art to business several years later. She says that it’s difficult to become a follower if you are used to leading. She also recently spoke at 3% conference.

She is a big promoter of the ad that you are as good as the last ad you manage. Lori says that for her to make money, she must first make her clients’ money. She acknowledges that she did not become profitable instantly and she took some time before she could reap some profits. Among the books that inspire Lori Senecal most are books touching on Steve Jobs. She says that there are a lot of leadership skills that can be learned from the Apple founder. Lori is active on social media such as Facebook, Twitter and website


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Custom Packages to Meet Diverse Client Needs

NextBank is a financial service company that offers mortgage banking, institutional services, and commercial banking services to its clients. The company was formed by banking professionals who came together to form simple and honest ideas for financial services. The mission of the company is commitment to its clients through industry leadership and to deliver uncommon value for every opportunity.

It offers its clients access to sophisticated custom tailored solutions that are delivered by experienced professionals who have a proven track record of success. It has served the community since 1922. NextBank is focused on long term relationships with its partners and goes the extra mile to provide additional warehouse lines for its clients to allow them fund loans more efficiently. They have customised solutions that meets each client’s unique needs due to their dedication to meeting the client’s needs.

NextBank offers a range of deposit and lending products to meet both short- term and long-term needs of corporations and financial institutions. It helps its clients to optimize cash flow and develop complex financial structures that support expansion and business efficiency.

NextBank offers competitive prices for correspondent channels and warehouse lines of credit. The company partners with institutions to establish the best approach for their specific banking and financial needs. It also offers specialised accounts for financial institutions and depository services to its clients. NextBank serves institutions by helping them improve on productivity and gain more visibility of their cash flow thus improving liquidity of the firms and expanding their revenue potential. Public funds depositors have access to tailored depository services. It focuses on enhancement and preservation of property value through minimal operating costs and improved tenant experience.